hypogonadism

Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

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Study Counts

Type	Study_count
Total_Studies	228
interventional	191
Observational	35
Registry	2

Studies over Time by Start Date

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Interventional Trials

Intervention Type

intervention_type	Study_Count
Drug	125
Drug|placebo	46
Combination Product	4
Behavioral|Drug	2
Biological	2
Dietary Supplement	2
Drug|Other|placebo	2
Drug|Procedure	2
Procedure	2
Device|Drug	1
Dietary Supplement|Drug|placebo	1
Drug|Other	1
placebo|Radiation	1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country	Study_Count
United States	115
NA	16
Turkey	8
United Kingdom	6
United States|Canada	5
Denmark	4
Italy	4
China	3
Australia	2
Brazil	2
France	2
Germany	2
India	2
Spain	2
United States|Germany	2
Austria	1
Belarus	1
Brazil|Denmark|Italy|Mexico|Russian Federation|South Africa	1
Canada	1
Italy|United States|Spain|United Kingdom	1
Korea, Republic of	1
Netherlands	1
Norway	1
Slovakia	1
Slovenia	1
Switzerland	1
Thailand	1
United States|Argentina|Canada|Germany|Italy|Korea, Republic of|Puerto Rico|Spain|United Kingdom	1
United States|Australia|France|Germany|Sweden|United Kingdom	1
United States|Chile	1
United States|Puerto Rico	1

Sites per Study

Site_count	Study_Count
1	117
2	18
3	7
4	2
5	1
6	1
7	3
8	3
9	2
11	2
12	1
13	1
14	2
15	1
16	2
17	1
18	5
19	2
20	1
21	1
22	1
23	1
27	2
28	1
30	3
31	1
35	1
36	1
37	1
45	2
63	1
70	1
85	1
388	1

Phase

Phase	Study_Count
Phase 2	52
Phase 3	47
Phase 4	39
Phase 1	25
N/A	21
Phase 1/Phase 2	4
Phase 2/Phase 3	3

Number of Arms

Number_of_Arms	Count_of_Studies
1	50
2	69
3	23
4	14
5	2
6	5
10	1
NA	27

Enrollment Metrics by Phase

Measure	N.A	Phase.1	Phase.1.Phase.2	Phase.2	Phase.2.Phase.3	Phase.3	Phase.4
Min.	10.0000	6.000	8.0	3.00	31.00000	6.0000	4.0000
1st Qu.	30.0000	19.750	12.5	22.00	43.50000	77.0000	40.0000
Median	50.0000	34.000	14.5	46.00	56.00000	144.0000	100.0000
Mean	122.0952	89.875	19.0	67.70	58.33333	166.6383	267.7692
3rd Qu.	158.0000	65.000	21.0	81.75	72.00000	188.0000	147.0000
Max.	800.0000	496.000	39.0	322.00	88.00000	715.0000	6000.0000

Trial Group Type

group_type	Group_Count
Experimental	205
Active Comparator	70
Placebo Comparator	55
NA	27
Other	22
No Intervention	11

Intervention Model

intervention_model	Study_Count
Parallel Assignment	105
Single Group Assignment	60
Crossover Assignment	22
Factorial Assignment	2
NA	2

Primary Purpose

primary_purpose	Study_Count
Treatment	152
Other	10
Basic Science	8
Diagnostic	6
NA	5
Prevention	3
Screening	3
Supportive Care	3
Health Services Research	1

Observational Studies

Studies by Country

Country	Study_Count
United States	13
Germany	4
NA	3
Denmark	2
Italy	2
Switzerland	2
Turkey	2
Australia	1
Canada|Croatia|Germany|Kuwait|Romania|Russian Federation|Saudi Arabia|Slovenia|United Arab Emirates	1
France	1
Germany|Italy|Netherlands|Spain|Sweden|United Kingdom	1
Jordan|Australia|Austria|Bulgaria|Colombia|Czech Republic|Estonia|Germany|Hong Kong|Indonesia|Italy|Kazakhstan|Korea, Republic of|Latvia|Lebanon|Lithuania|Macedonia, The Former Yugoslav Republic of|Malaysia|Malta|Mexico|Moldova, Republic of|Philippines|Romania|Russian Federation|Saudi Arabia|Singapore|Slovenia|Spain|Taiwan|Thailand|Turkey|Ukraine|United Kingdom	1
Netherlands	1
Russian Federation	1

Sites per Study

Site_count	Study_Count
1	28
2	3
25	1
33	1
64	1
331	1

Enrollment Metrics

Measure	Observational
Min	20.000
1st Qu	62.500
Median	178.500
Mean	1288.794
3rd Qu	521.750
Max	27778.000

Observation Model

observational_model	Study_Count
Cohort	14
NA	7
Case-Only	5
Case Control	5
Case-Control	3
Ecologic or Community	1

Time Perspective

time_perspective	Study_Count
Prospective	19
Cross-Sectional	10
NA	5
Retrospective	1

Registries

Studies by Country

Country	Study_Count
Turkey	1
United States|Australia	1

Sites per Study

Site_count	Study_Count
1	1
2	1

Enrollment Metrics

Measure	Registries
Min	16
1st Qu	5012
Median	10008
Mean	10008
3rd Qu	15004
Max	20000

Registry Model

observational_model	Study_Count
Case-Only	2

Time Perspective

time_perspective	Study_Count
Prospective	2

Follow-up

target_duration	Study_Count
100 Years	1
6 Months	1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT03282682	Strength Training as a Supplemental Therapy of Androgen Deficiency of the Aging Male	https://ClinicalTrials.gov/show/NCT03282682	Completed	Comenius University	2019-05-30
NCT03242408	Dosing Flexibility Study of Oral Testosterone Undecanoate (TU, LPCN 1021)	https://ClinicalTrials.gov/show/NCT03242408	Completed	Lipocine Inc.	2017-05-31
NCT03203681	Natesto Effects on Testosterone, Luteinizing Hormone, Follicle Stimulating Hormone and Semen Parameters	https://ClinicalTrials.gov/show/NCT03203681	Completed	University of Miami	2020-06-01
NCT03126656	Effects of Testosterone on Myocardial Repolarization	https://ClinicalTrials.gov/show/NCT03126656	Completed	University of Roma La Sapienza	2017-04-30
NCT03091348	Subcutaneous vs. Intramuscular Testosterone	https://ClinicalTrials.gov/show/NCT03091348	Completed	Men’s Health Boston	2017-11-21
NCT03057899	Efficacy of Fenugreek Seed and Lespedeza Cuneata in TDS	https://ClinicalTrials.gov/show/NCT03057899	Completed	Pusan National University Hospital	2015-11-30
NCT02966652	Study to Compare DITEST to Testosterone Undecanoate in Adult Men With Hypogonadism	https://ClinicalTrials.gov/show/NCT02966652	Completed	Diurnal Limited	2018-10-04
NCT02959853	Aromatase Inhibitors and Weight Loss in Severely Obese Hypogonadal Male Veterans (Pilot)	https://ClinicalTrials.gov/show/NCT02959853	Completed	Baylor College of Medicine	2018-11-20
NCT02956447	Administration of Kisspeptin in Patients With Hyperprolactinemia	https://ClinicalTrials.gov/show/NCT02956447	Recruiting	Massachusetts General Hospital	2022-03-31
NCT02953834	Kisspeptin Influence on Glucose Homeostasis	https://ClinicalTrials.gov/show/NCT02953834	Recruiting	Massachusetts General Hospital	2022-12-31
NCT02937740	Open-Label Study, Evaluating Patient Satisfaction and Symptom Improvement When Treating Male Hypogonadism With Natestoâ„¢	https://ClinicalTrials.gov/show/NCT02937740	Completed	Acerus Pharmaceuticals Corporation	2017-10-31
NCT02921386	The Effect of Various Amounts of Fat on PK of Oral Testosterone Undecanoate	https://ClinicalTrials.gov/show/NCT02921386	Completed	Clarus Therapeutics, Inc.	2017-01-21
NCT02908074	A 6 Month Safety Extension Study of MBGS205	https://ClinicalTrials.gov/show/NCT02908074	Completed	Mereo BioPharma	2018-09-08
NCT02847806	Effects of Replacement Therapy With Sexual Steroid Hormones on the Insulin Sensitivity of Hypogonadal Man	https://ClinicalTrials.gov/show/NCT02847806	Completed	University Hospital, Caen	2015-12-31
NCT02777242	Safety of Subcutaneous Testosterone Enanthate in Adult Male Hypogonadism	https://ClinicalTrials.gov/show/NCT02777242	Completed	Antares Pharma Inc.	2016-08-31
NCT02758431	Cardiovascular Outcomes of Low Testosterone	https://ClinicalTrials.gov/show/NCT02758431	Recruiting	University of Colorado, Denver	2021-01-31
NCT02748005	Evaluation of Furosap in Human Volunteers	https://ClinicalTrials.gov/show/NCT02748005	Completed	Chemical Resources	2015-07-31
NCT02733133	Product Transference Study of Testagen™ TDS®-Testosterone	https://ClinicalTrials.gov/show/NCT02733133	Enrolling by invitation	Transdermal Delivery Solutions Corp	2020-10-31
NCT02730169	Safety and Efficacy of BGS649 in Male Obese Subjects With Hypogonadotropic Hypogonadism	https://ClinicalTrials.gov/show/NCT02730169	Completed	Mereo BioPharma	2018-02-15
NCT02722278	A Study of Oral Testosterone Undecanoate (TU) in Hypogonadal Men	https://ClinicalTrials.gov/show/NCT02722278	Completed	Clarus Therapeutics, Inc.	2016-11-30
NCT02702882	The Efficacy Study of FUROSAP: A Testosterone Booster Supplement In Humans.	https://ClinicalTrials.gov/show/NCT02702882	Completed	Chemical Resources	2017-03-31
NCT02697188	Pilot Pharmacokinetic Study of Oral Testosterone Ester Formulations in Hypogonadal Men	https://ClinicalTrials.gov/show/NCT02697188	Completed	Clarus Therapeutics, Inc.	2008-04-30
NCT02672592	Effects of Interleukin-1 Beta on Low Testosterone Levels in Men With Obesity and Metabolic Syndrome	https://ClinicalTrials.gov/show/NCT02672592	Completed	University Hospital, Basel, Switzerland	2017-06-30
NCT02670343	Phlebotomy Study of Testosterone Undecanoate	https://ClinicalTrials.gov/show/NCT02670343	Completed	Clarus Therapeutics, Inc.	2016-03-31
NCT02653092	Reprometabolic Syndrome Mediates Subfertility in Obesity	https://ClinicalTrials.gov/show/NCT02653092	Recruiting	University of Colorado, Denver	2020-02-29
NCT02651688	A Multi-Center Study in Men With Acquired Hypogonadotropic Hypogonadism to Compare Changes in Body Composition and Metabolic Parameters With Diet and Exercise in Conjunction With Treatment With 12.5 mg or 25 mg Enclomiphene	https://ClinicalTrials.gov/show/NCT02651688	Completed	Repros Therapeutics Inc.	2017-05-02
NCT02514629	Testosterone, Metformin, or Both, for Hypogonadism in Obese Males	https://ClinicalTrials.gov/show/NCT02514629	Completed	Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud	2016-07-12
NCT02504541	Subcutaneous Testosterone Enanthate Safety in Adult Men Diagnosed With Hypogonadism	https://ClinicalTrials.gov/show/NCT02504541	Completed	Antares Pharma Inc.	2016-06-30
NCT02380755	Clomiphene Citrate for the Treatment of Obesity Related Male Hypogonadism	https://ClinicalTrials.gov/show/NCT02380755	Completed	University of Sao Paulo	2017-01-31
NCT02367105	Lifestyle Intervention and Testosterone Replacement in Obese Seniors	https://ClinicalTrials.gov/show/NCT02367105	Completed	VA Office of Research and Development	2019-07-31
NCT02366975	TRT on BPH Hypoganadal MetS Patients. Florence-PROTEST	https://ClinicalTrials.gov/show/NCT02366975	Completed	University of Florence	2017-01-31
NCT02274181	An Open-Label, Single-Dose Study to Assess the Absorption, Metabolism, Excretion, and Mass Balance of Radiolabeled Androxal in Healthy Male Subjects After Oral Administration	https://ClinicalTrials.gov/show/NCT02274181	Completed	Repros Therapeutics Inc.	2015-01-31
NCT02248701	Testosterone Plus Finasteride Treatment After Spinal Cord Injury	https://ClinicalTrials.gov/show/NCT02248701	Recruiting	VA Office of Research and Development	2021-05-31
NCT02233751	Pharmacokinetic Study of Subcutaneous Testosterone Enanthate	https://ClinicalTrials.gov/show/NCT02233751	Completed	Antares Pharma Inc.	2014-10-31
NCT02222558	Oral Testosterone for the Treatment of Hypogonadism in Males	https://ClinicalTrials.gov/show/NCT02222558	Completed	TesoRx Pharma, LLC	2015-04-30
NCT02171390	Endothelial Dysfunction, Inflammation and Insulin Resistance in Congenital Hypogonadism and Effect of Testosteron Replacement Therapy	https://ClinicalTrials.gov/show/NCT02171390	Completed	Gulhane School of Medicine	2012-06-30
NCT02159469	Subcutaneous Testosterone Replacement Efficacy and Safety in Adult Men Diagnosed With Hypogonadism	https://ClinicalTrials.gov/show/NCT02159469	Completed	Antares Pharma Inc.	2015-02-28
NCT02154477	Effect of Intranasal Insulin on LH Concentrations in Man	https://ClinicalTrials.gov/show/NCT02154477	Completed	Texas Tech University Health Sciences Center	2017-12-31
NCT02149264	A Clinical Trial to Evaluate the Efficacy and Safety of Testosterone Gel in Adult Hypogonadal Males	https://ClinicalTrials.gov/show/NCT02149264	Completed	Ferring Pharmaceuticals	2015-05-31
NCT02137265	Assessing the Efficacy of Clomiphene Citrate in Patients With Azoospermia and Hypoandrogenism	https://ClinicalTrials.gov/show/NCT02137265	Recruiting	University of Illinois at Chicago	2019-10-31
NCT02111473	The Effect of Testosteron Replacement Treatment on the Fibroblast Growth Factor-23, Asymmetric Dimethylarginine and Vitamin D Levels in the Congenital Hypogonadotropic Hypogonadism	https://ClinicalTrials.gov/show/NCT02111473	Completed	Gulhane School of Medicine	2012-05-31
NCT02111434	Visceral Adiposity Index and Triglyceride/High-density Lipoprotein Cholesterol Ratio in the Congenital Hypogonadotropic Hypogonadism and Effect of Testosteron Treatment	https://ClinicalTrials.gov/show/NCT02111434	Completed	Gulhane School of Medicine	2014-04-30
NCT02110368	Bioequivalence Study of Test and Reference Testosterone Topical Gel, 1.62% Metered Pump in Testosterone Deficient Adult Male Subjects Under Fasting Conditions	https://ClinicalTrials.gov/show/NCT02110368	Completed	Amneal Pharmaceuticals, LLC	2014-03-31
NCT02102646	MRI Substudy; Metabolic Changes Due to Iatrogenic Hypogonadism	https://ClinicalTrials.gov/show/NCT02102646	Completed	Herlev Hospital	2015-10-31
NCT02081300	Safety and Efficacy of Oral LPCN 1021 in Men With Low Testosterone or Hypogonadism	https://ClinicalTrials.gov/show/NCT02081300	Completed	Lipocine Inc.	2015-05-31
NCT01270841	Normalization of Morning Testosterone Levels in Men With Secondary Hypogonadism	https://ClinicalTrials.gov/show/NCT01270841	Completed	Repros Therapeutics Inc.	2011-12-31
NCT01993225	A Randomized, Double Blind, Placebo-Controlled, Multi-Center Phase III Study in Men With Acquired Hypogonadotropic Hypogonadism to Compare Changes in Testosterone and Sperm Concentration Following Treatment With 12.5 mg or 25 mg Androxal or AndroGel 1.62%	https://ClinicalTrials.gov/show/NCT01993225	Completed	Repros Therapeutics Inc.	2014-08-31
NCT01993212	A Randomized, Double Blind, Placebo-Controlled, Multi-Center Phase III Study in Men With Acquired Hypogonadotropic Hypogonadism to Compare Changes in Testosterone and Sperm Concentration Following Treatment With 12.5 mg or 25 mg Androxal or AndroGel 1.62%	https://ClinicalTrials.gov/show/NCT01993212	Completed	Repros Therapeutics Inc.	2014-09-30
NCT01976728	LutrePulse Hypogonadotropic Hypogonadism	https://ClinicalTrials.gov/show/NCT01976728	Completed	Ferring Pharmaceuticals	2018-02-23
NCT01952782	Neuropeptides in Human Reproduction	https://ClinicalTrials.gov/show/NCT01952782	Recruiting	Massachusetts General Hospital	2022-08-31
NCT01923870	Evaluation of the Pharmacokinetics and Safety of Androxal in Male Subjects With Impaired Hepatic Function	https://ClinicalTrials.gov/show/NCT01923870	Completed	Repros Therapeutics Inc.	2014-01-31
NCT01923857	Evaluation of Pharmacokinetic and Safety Profile of Androxal in Male Subjects With Impaired Renal Function	https://ClinicalTrials.gov/show/NCT01923857	Completed	Repros Therapeutics Inc.	2014-08-31
NCT01919294	Testosterone Replacement in Non-alcoholic Steatohepatitis (TEREPINS)	https://ClinicalTrials.gov/show/NCT01919294	Completed	Sheffield Teaching Hospitals NHS Foundation Trust	2017-01-30
NCT01894308	A Dose Ranging Study to Examine Testagen® TDS-Testosterone 5%	https://ClinicalTrials.gov/show/NCT01894308	Enrolling by invitation	Transdermal Delivery Solutions Corp	2020-11-30
NCT01893281	The Effect of Testosterone Topical Solution (LY900011) in Hypogonadal Men With Suboptimal Response to a Topical Testosterone Gel	https://ClinicalTrials.gov/show/NCT01893281	Completed	Eli Lilly and Company	2014-01-31
NCT01887418	Pharmacokinetic Study of Testosterone Enanthate	https://ClinicalTrials.gov/show/NCT01887418	Completed	Antares Pharma Inc.	2014-01-31
NCT01880086	Clomiphene Citrate for the Treatment of Low Testosterone Associated With Chronic Opioid Pain Medication Administration	https://ClinicalTrials.gov/show/NCT01880086	Completed	Weill Medical College of Cornell University	2016-03-31
NCT01873989	Testosterone Replacement for Male Opioid Agonist Maintained Patients	https://ClinicalTrials.gov/show/NCT01873989	Completed	Yale University	2015-01-31
NCT01816295	A Study in Men With Low Testosterone to Measure the Effects of Testosterone Solution on Testosterone Levels, Sex Drive and Energy	https://ClinicalTrials.gov/show/NCT01816295	Completed	Eli Lilly and Company	2014-10-31
NCT01765179	Safety and Efficacy Trial of Testosterone Undecanoate	https://ClinicalTrials.gov/show/NCT01765179	Completed	Clarus Therapeutics, Inc.	2013-07-31
NCT01748370	Vitamin D Treatment and Hypogonadism in Men	https://ClinicalTrials.gov/show/NCT01748370	Completed	Medical University of Graz	2017-11-12
NCT01739595	Phase III Study to Evaluate Morning Testosterone Normalization in Overweight Men With Secondary Hypogonadism	https://ClinicalTrials.gov/show/NCT01739595	Completed	Repros Therapeutics Inc.	2013-09-30
NCT01739582	An Extension Study of Enclomiphene Citrate in the Treatment of Men With Secondary Hypogonadism	https://ClinicalTrials.gov/show/NCT01739582	Completed	Repros Therapeutics Inc.	2014-04-30
NCT01717768	Oral Testosterone for the Treatment of Hypogonadism	https://ClinicalTrials.gov/show/NCT01717768	Completed	TesoRx Pharma, LLC	2014-08-31
NCT01709331	A Study of the Efficacy and Safety of Corifollitropin Alfa (MK-8962) in Combination With Human Chorionic Gonadotropin (hCG) in Adult Men With Hypogonadotropic Hypogonadism (HH) (P07937)	https://ClinicalTrials.gov/show/NCT01709331	Completed	Merck Sharp & Dohme Corp.	2015-04-08
NCT01703741	A Multicenter Extension Trial to Evaluate the Safety of Testosterone Gel	https://ClinicalTrials.gov/show/NCT01703741	Completed	Ferring Pharmaceuticals	2013-10-31
NCT01699178	Open-label, Follow-up Study of Oral Testosterone Undecanoate in Hypogonadal Men	https://ClinicalTrials.gov/show/NCT01699178	Completed	Clarus Therapeutics, Inc.	2014-04-30
NCT01665599	A Clinical Trial to Evaluate the Efficacy and Safety of Testosterone Gel	https://ClinicalTrials.gov/show/NCT01665599	Completed	Ferring Pharmaceuticals	2013-04-30
NCT01623570	Clinical Outcomes in WHO Type I Anovulatory Women Using r-hFSH+r-hLH in a 2:1 Ratio or hMG-HP	https://ClinicalTrials.gov/show/NCT01623570	Completed	Centro Riproduzione e Andrologia	2012-05-31
NCT01619683	Assessment of the Effects of Enclomiphene Citrate on Bone Mineral Density in Men With Secondary Hypogonadism	https://ClinicalTrials.gov/show/NCT01619683	Completed	Repros Therapeutics Inc.	2014-09-30
NCT01601327	Effects of Medications in Patients With Hypogonadism	https://ClinicalTrials.gov/show/NCT01601327	Completed	Gulhane School of Medicine	2012-03-31
NCT04320745	A Study to Evaluate Androderm’s Effect on Blood Pressure in Adult Hypogonodal Male Participants.	https://ClinicalTrials.gov/show/NCT04320745	Recruiting	Allergan	2020-08-27
NCT01534208	Safety Study of Enclomiphene Citrate in the Treatment of Men With Secondary Hypogonadism	https://ClinicalTrials.gov/show/NCT01534208	Completed	Repros Therapeutics Inc.	2013-10-31
NCT01533129	The Effect of Testosterone Replacement on Endothelial Dysfunction, Inflammation and Insulin Resistance in Male Hypogonadotrophic Hypogonadism	https://ClinicalTrials.gov/show/NCT01533129	Completed	Gulhane School of Medicine	2011-04-30
NCT01532414	Phase III Study to Evaluated Morning Testosterone Normalization in Men With Secondary Hypogonadism	https://ClinicalTrials.gov/show/NCT01532414	Completed	Repros Therapeutics Inc.	2013-03-31
NCT01454011	The Effect of Testosterone Replacement on the High Density Lipoprotein Cholesterol Subgroups	https://ClinicalTrials.gov/show/NCT01454011	Completed	Gulhane School of Medicine	2011-02-28
NCT01438073	Elucidating Kisspeptin Physiology by Blocking Kisspeptin Signaling	https://ClinicalTrials.gov/show/NCT01438073	Recruiting	Massachusetts General Hospital	2023-09-30
NCT01438034	Kisspeptin in the Evaluation of Delayed Puberty	https://ClinicalTrials.gov/show/NCT01438034	Recruiting	Massachusetts General Hospital	2023-11-30
NCT01446042	Safety and Efficacy of Intranasal TBS-1 Treatment of Male Hypogonadism	https://ClinicalTrials.gov/show/NCT01446042	Completed	Acerus Pharmaceuticals Corporation	2012-12-31
NCT01419236	A Study of Ejaculatory Dysfunction in Men With Low Testosterone Levels	https://ClinicalTrials.gov/show/NCT01419236	Completed	Eli Lilly and Company	2013-12-31
NCT01403532	Sequential Therapy for Hypogonadotropic Hypogonadism	https://ClinicalTrials.gov/show/NCT01403532	Completed	Shanghai Jiao Tong University School of Medicine	2012-12-31
NCT01403116	Safety and Efficacy Trial of Oral Testosterone Undecanoate (TU) in Hypogonadal Men	https://ClinicalTrials.gov/show/NCT01403116	Completed	Clarus Therapeutics, Inc.	2013-09-30
NCT01386606	The Effect on Androxal Versus Androgel on Morning Testosterone in Men With Secondary Hypogonadism (Low Testosterone)	https://ClinicalTrials.gov/show/NCT01386606	Completed	Repros Therapeutics Inc.	2011-10-31
NCT01386567	A One Year Open Label Study for the Treatment of Hypogonadism (Low Testosterone) in Men Who Have Completed ZA-203	https://ClinicalTrials.gov/show/NCT01386567	Completed	Repros Therapeutics Inc.	2013-01-31
NCT01378299	CYP19A1 (Cytochrome P450 Family 19 Subfamily A Member 1) Gene and Pharmacogenetics of Response to Testosterone Therapy	https://ClinicalTrials.gov/show/NCT01378299	Completed	VA Office of Research and Development	2016-11-07
NCT01370369	Efficacy, Pharmacokinetics and Safety of Testosterone	https://ClinicalTrials.gov/show/NCT01370369	Completed	Ferring Pharmaceuticals	2011-07-31
NCT01323140	Pharmacokinetics, Metabolism, Efficacy, and Safety Study of Two Testosterone Matrix Transdermal Systems	https://ClinicalTrials.gov/show/NCT01323140	Completed	Watson Pharmaceuticals	2011-07-31
NCT04274894	A Study of the Effect of Topical Testosterone Replacement Therapy on Blood Pressure in Adult Male Participants With Hypogonadism	https://ClinicalTrials.gov/show/NCT04274894	Recruiting	AbbVie	2020-12-17
NCT04049331	Testosterone Replacement in Male Cancer Survivors With Fatigue and Low Testosterone	https://ClinicalTrials.gov/show/NCT04049331	Recruiting	Seattle Institute for Biomedical and Clinical Research	2024-12-01
NCT03245827	Hypogonadotropic Hypogonadism in Obese Young Males	https://ClinicalTrials.gov/show/NCT03245827	Recruiting	St. Louis University	2021-12-31
NCT03933618	Anastrazole and Clomiphene to Evaluate Hypogonadal Symptoms and Erectile Function	https://ClinicalTrials.gov/show/NCT03933618	Completed	Albany Medical College	2017-03-08
NCT03887936	Testosterone Therapy and Bone Quality in Men With Diabetes and Hypogonadism	https://ClinicalTrials.gov/show/NCT03887936	Recruiting	VA Office of Research and Development	2024-09-30
NCT03868059	Ambulatory Blood Pressure Monitoring in Oral Testosterone Undecanoate (TU, LPCN 1021) Treated Hypogonadal Men	https://ClinicalTrials.gov/show/NCT03868059	Completed	Lipocine Inc.	2019-02-19
NCT03792477	A Bioequivalence Study of Testosterone Cypionate in Hypogonadal Males	https://ClinicalTrials.gov/show/NCT03792477	Completed	Pfizer	2020-04-02
NCT03792321	Study on Effects of Testosterone Replacement Therapy in Hypogonadal Type 2 Diabetic Patients" (SETH2)	https://ClinicalTrials.gov/show/NCT03792321	Completed	University Medical Centre Ljubljana	2015-03-05
NCT03687606	Efficacy and Safety of Long Term Use of hCG or hCG Plus hMG in Males With Isolated Hypogonadotropic Hypogonadism (IHH)	https://ClinicalTrials.gov/show/NCT03687606	Recruiting	Tongji Hospital	2024-10-01
NCT03619330	Testosterone Replacement Therapy and Liraglutide Effects on Weight Loss in Hypogonadism.	https://ClinicalTrials.gov/show/NCT03619330	Completed	University Medical Centre Ljubljana	2015-08-31
NCT03541395	Testosterone-Dependent Effects on Protein Biomarkers From Healthy Males	https://ClinicalTrials.gov/show/NCT03541395	Completed	Lund University	2015-06-30
NCT03518034	A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men	https://ClinicalTrials.gov/show/NCT03518034	Recruiting	AbbVie	2022-06-30
NCT04456296	A Study of the Effect of Testosterone Replacement Therapy on Blood Pressure in Adult Male Participants With Hypogonadism	https://ClinicalTrials.gov/show/NCT04456296	Recruiting	Endo Pharmaceuticals	2022-04-30
NCT03490513	Aromatase Inhibitors and Weight Loss in Severely Obese Men With Hypogonadism	https://ClinicalTrials.gov/show/NCT03490513	Recruiting	Baylor College of Medicine	2023-04-14
NCT03418896	Extragonadal Effects of hCG on Calcium Homeostasis	https://ClinicalTrials.gov/show/NCT03418896	Active, not recruiting	Rigshospitalet, Denmark	2020-10-31
NCT01252745	Efficacy of an Intranasal Testosterone Product	https://ClinicalTrials.gov/show/NCT01252745	Completed	Acerus Pharmaceuticals Corporation	2010-11-30
NCT01228071	Time to Eugonadal Range, Time to Steady State and Drying Time	https://ClinicalTrials.gov/show/NCT01228071	Completed	Endo Pharmaceuticals	2011-05-31
NCT01206270	Androgen for Leydig Cell Proliferation	https://ClinicalTrials.gov/show/NCT01206270	Completed	University of Roma La Sapienza	2017-06-30
NCT01191320	Study to Evaluate the Efficacy of Androxal in Controlling Blood Glucose in Men With Type-2 Diabetes Mellitus	https://ClinicalTrials.gov/show/NCT01191320	Completed	Repros Therapeutics Inc.	2011-12-31
NCT01160341	Metabolic Syndrome Criteria and the Effect of Testosterone Treatment in Young Men With Hypogonadism	https://ClinicalTrials.gov/show/NCT01160341	Completed	Gulhane School of Medicine	2010-01-31
NCT01133548	Pharmacokinetic and Comparative Bioavailability Study of Testosterone Absorption After Administration of Testosterone Gel 1.62% to the Upper Arms/Shoulders Using an Application Site Rotation or a Combination of Application Sites in Hypogonadal Males	https://ClinicalTrials.gov/show/NCT01133548	Completed	AbbVie	2010-07-31
NCT01127659	Testosterone Replacement in Men With Diabetes and Obesity	https://ClinicalTrials.gov/show/NCT01127659	Completed	University at Buffalo	2015-03-31
NCT01123278	Testosterone Replacement in Metabolic Syndrome and Inflammation	https://ClinicalTrials.gov/show/NCT01123278	Completed	University of Roma La Sapienza	2014-10-31
NCT01107067	Testosterone Replacement Therapy Decreases Plasma Paraoxonase 1 Enzyme Activity In Male Patients With Hypogonadism	https://ClinicalTrials.gov/show/NCT01107067	Completed	Gulhane School of Medicine	2009-12-31
NCT01104246	Dose Titration Investigation of the Pharmacokinetics of Testosterone Transdermal Systems in Hypogonadal Men	https://ClinicalTrials.gov/show/NCT01104246	Completed	Watson Pharmaceuticals	2010-09-30
NCT01084265	A Study Using Recombinant Human Luteinizing Hormone (r-hLH, Luveris®) in the Treatment of Chinese Women With Hypogonadotropic Hypogonadism	https://ClinicalTrials.gov/show/NCT01084265	Completed	Merck KGaA, Darmstadt, Germany	2005-12-31
NCT01067365	Study to Evaluate the Safety and Efficacy of Androxal Treatment in Men With Secondary Hypogonadism	https://ClinicalTrials.gov/show/NCT01067365	Completed	Repros Therapeutics Inc.	2007-05-31
NCT01061970	Efficacy and Safety of Fispemifene in the Treatment of Hypogonadal Men With Chronic Obstructive Pulmonary Disease That Are on Oral Glucocorticoid Therapy	https://ClinicalTrials.gov/show/NCT01061970	Completed	QuatRx Pharmaceuticals Company	NA
NCT00998933	Study of Serum Testosterone Levels in Non-dosed Females After Secondary Exposure	https://ClinicalTrials.gov/show/NCT00998933	Completed	Solvay Pharmaceuticals	2009-10-31
NCT00975650	Efficacy and Tolerability of an Intra-Nasal Testosterone Product	https://ClinicalTrials.gov/show/NCT00975650	Completed	Acerus Pharmaceuticals Corporation	2010-05-31
NCT00962637	Study to Evaluate the Safety and Efficacy of Androxalâ„¢ Treatment in Men With Secondary Hypogonadism	https://ClinicalTrials.gov/show/NCT00962637	Completed	Repros Therapeutics Inc.	2007-05-31
NCT00957528	Cycled Testosterone Replacement Study	https://ClinicalTrials.gov/show/NCT00957528	Completed	The University of Texas Medical Branch, Galveston	2008-12-31
NCT00924612	Study to Determine the Effect of Food on the Absorption of an Oral Testosterone Undecanoate Formulation	https://ClinicalTrials.gov/show/NCT00924612	Completed	Clarus Therapeutics, Inc.	2009-09-30
NCT00914823	Administration of Kisspeptin to Subjects With Reproductive Disorders	https://ClinicalTrials.gov/show/NCT00914823	Recruiting	Massachusetts General Hospital	2023-12-31
NCT00911586	Pharmacokinetic Study to Determine Time to Steady-state	https://ClinicalTrials.gov/show/NCT00911586	Completed	Clarus Therapeutics, Inc.	2009-09-30
NCT00857961	A Study of the Pharmacokinetics of Testosterone Metered Dose (MD)-Lotion Formulations	https://ClinicalTrials.gov/show/NCT00857961	Completed	Eli Lilly and Company	2008-01-31
NCT00857454	A Trial to Evaluate the Ongoing Skin Safety of Testosterone MD-Lotion Formulations	https://ClinicalTrials.gov/show/NCT00857454	Completed	Eli Lilly and Company	2009-08-31
NCT00857168	To Determine the Effects of Deodorant, Antiperspirant and Washing on the Pharmacokinetics of 2% Testosterone MD Lotion	https://ClinicalTrials.gov/show/NCT00857168	Completed	Acrux DDS Pty Ltd	2009-02-28
NCT00837616	Estrogen Dosing in Turner Syndrome: Pharmacology and Metabolism	https://ClinicalTrials.gov/show/NCT00837616	Completed	Nemours Children’s Clinic	2012-06-30
NCT03345797	Evaluation of Testosterone Nasal Gel in Hypogonadal Boys	https://ClinicalTrials.gov/show/NCT03345797	Recruiting	Acerus Pharmaceuticals Corporation	2020-11-30
NCT03973840	Assessment of Blood From Men Receiving Oral TU in Various Collection Tubes	https://ClinicalTrials.gov/show/NCT03973840	Completed	Clarus Therapeutics, Inc.	2018-07-31
NCT01560546	Testosterone Therapy of Men With Type 2 Diabetes Mellitus (T2DM)	https://ClinicalTrials.gov/show/NCT01560546	Completed	Odense University Hospital	2013-05-31
NCT03242590	Dosing Validation Study of Oral Testosterone Undecanoate (TU, LPCN 1021).	https://ClinicalTrials.gov/show/NCT03242590	Completed	Lipocine Inc.	2017-03-31
NCT03019575	Efficacy and Safety of Corifollitropin Alfa (MK-8962) in Combination With Human Chorionic Gonadotropin (hCG) in Adolescent Males With Hypogonadotropic Hypogonadism (HH)	https://ClinicalTrials.gov/show/NCT03019575	Completed	Merck Sharp & Dohme Corp.	2020-05-05
NCT03198728	Efficacy and Safety of Oral Testosterone Undecanoate in Hypogonadal Men	https://ClinicalTrials.gov/show/NCT03198728	Completed	Marius Pharmaceuticals	2020-05-01
NCT00752869	Efficacy Study for Use of Dutasteride (Avodart) With Testosterone Replacement	https://ClinicalTrials.gov/show/NCT00752869	Completed	The Miriam Hospital	2012-03-31
NCT00706719	To Evaluate Sperm Parameters in Men With Secondary Hypogonadism Previously Treated With Topical Testosterone	https://ClinicalTrials.gov/show/NCT00706719	Completed	Repros Therapeutics Inc.	2009-07-31
NCT00702650	A Titration Trial to Determine the Effectiveness of Testosterone MD-Lotion (Cutaneous Solution) Formulations	https://ClinicalTrials.gov/show/NCT00702650	Completed	Eli Lilly and Company	2009-07-31
NCT00697814	Clomiphene in Males With Prolactinomas and Persistent Hypogonadism	https://ClinicalTrials.gov/show/NCT00697814	Completed	Federal University of São Paulo	2005-06-30
NCT00695110	Pharmacokinetic Study of Oral Testosterone (T) Ester Formulations in Hypogonadal Men	https://ClinicalTrials.gov/show/NCT00695110	Completed	Clarus Therapeutics, Inc.	2008-12-31
NCT00663793	ORAL T-6: Oral Androgens in Man-6	https://ClinicalTrials.gov/show/NCT00663793	Completed	University of Washington	2009-05-31
NCT00647868	NASOBOL in Hypogonadal Men in Comparison to Testosterone Levels in Normal Healthy Male Volunteers	https://ClinicalTrials.gov/show/NCT00647868	Completed	Acerus Pharmaceuticals Corporation	2009-03-31
NCT00613782	Reandron in Diabetic Men Witn Low Testosterone Level	https://ClinicalTrials.gov/show/NCT00613782	Completed	Austin Health	2014-01-31
NCT00613288	Testosterone and Lipolysis, Insulin Sensitivity and Protein Metabolism	https://ClinicalTrials.gov/show/NCT00613288	Completed	University of Aarhus	2009-09-30
NCT00597051	Study of 3 Doses of ARD-0403 in Testosterone Deficient Men	https://ClinicalTrials.gov/show/NCT00597051	Completed	Ardana Bioscience Ltd	2006-02-28
NCT00522431	A Study of Fortigel Testosterone Gel 2% in Males With Low Testosterone	https://ClinicalTrials.gov/show/NCT00522431	Completed	Endo Pharmaceuticals	2008-03-31
NCT00504712	Testosterone for Peripheral Vascular Disease	https://ClinicalTrials.gov/show/NCT00504712	Completed	Barnsley Hospital	2009-12-31
NCT00493961	Studying the Effects of 7 Days of Gonadotropin Releasing Hormone (GnRH) Treatment in Men With Hypogonadism	https://ClinicalTrials.gov/show/NCT00493961	Active, not recruiting	Massachusetts General Hospital	2022-02-28
NCT00487734	Effect of Testosterone Replacement on Insulin Resistance	https://ClinicalTrials.gov/show/NCT00487734	Completed	McGuire Research Institute	2010-10-31
NCT00475501	5-Alpha Reductase and Anabolic Effects of Testosterone	https://ClinicalTrials.gov/show/NCT00475501	Completed	VA Office of Research and Development	2012-03-31
NCT00470990	Effect of Varying Testosterone Levels on Insulin Sensitivity in Normal and IHH Men	https://ClinicalTrials.gov/show/NCT00470990	Completed	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	2008-06-30
NCT00467870	Long-term Safety Study of Intramuscular Injections of 750 mg and 1000 mg Testosterone Undecanoate in Hypogonadal Men	https://ClinicalTrials.gov/show/NCT00467870	Completed	Endo Pharmaceuticals	2009-07-31
NCT00456274	Baselines in Reproductive Disorders	https://ClinicalTrials.gov/show/NCT00456274	Recruiting	Massachusetts General Hospital	2020-09-30
NCT00452322	Safety of Testosterone Undecanoate i.m. in Hypogonadal Men	https://ClinicalTrials.gov/show/NCT00452322	Completed	University Hospital Muenster	NA
NCT00448955	Open-Label Study of ARD-0403 in Testosterone Deficient Men	https://ClinicalTrials.gov/show/NCT00448955	Completed	Ardana Bioscience Ltd	2008-02-29
NCT00434824	Effects of Andriol Testocaps in Symptomatic Late-Onset Hypogonadism (43203)	https://ClinicalTrials.gov/show/NCT00434824	Completed	Merck Sharp & Dohme Corp.	2004-07-31
NCT00433199	Testosterone Treatment for Hypogonadal Men	https://ClinicalTrials.gov/show/NCT00433199	Completed	Abbott	2007-10-31
NCT00431197	Steady-State Feedback Actions of Testosterone on Luteinizing Hormone Secretion in Young and Older Men	https://ClinicalTrials.gov/show/NCT00431197	Completed	Mayo Clinic	2007-12-31
NCT00421460	The Therapy of Nebido as Mono or in Combination With PDE-5 Inhibitors in Hypogonadal Patients With Erectile Dysfunction	https://ClinicalTrials.gov/show/NCT00421460	Completed	Chulalongkorn University	2011-01-31
NCT00415571	Efficacy and Safety Evaluating Fispemifene in the Treatment of Hypogonadal Men With Erectile Dysfunction Unresponsive to PDE5 Inhibitors	https://ClinicalTrials.gov/show/NCT00415571	Completed	QuatRx Pharmaceuticals Company	NA
NCT00400335	Study On Bioavailability And Pharmacokinetics Of Various Doses Of Testosterone Administered With And Without Dutasteride	https://ClinicalTrials.gov/show/NCT00400335	Completed	GlaxoSmithKline	NA
NCT00398580	28-Day Study of Testosterone Co-administered With Dutasteride in Hypogonadal Men	https://ClinicalTrials.gov/show/NCT00398580	Completed	GlaxoSmithKline	2007-10-31
NCT00392912	Effect of Testosterone Therapy in Men With Alzheimer’s Disease and Low Testosterone	https://ClinicalTrials.gov/show/NCT00392912	Completed	VA Medical Center, Houston	2009-11-30
NCT00392756	Examination of Idiopathic Hypogonadotropic Hypogonadism (IHH)and Kallmann Syndrome (KS)	https://ClinicalTrials.gov/show/NCT00392756	Recruiting	Massachusetts General Hospital	2022-02-28
NCT00392457	Investigating the Regulation of Reproductive Hormones in Adult Men	https://ClinicalTrials.gov/show/NCT00392457	Completed	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)	2007-02-28
NCT00383656	Pulsatile GnRH in Anovulatory Infertility	https://ClinicalTrials.gov/show/NCT00383656	Recruiting	Massachusetts General Hospital	2020-09-30
NCT00372008	Pharmacokinetics of Testosterone Lotion in the Treatment of Hypogonadal Males	https://ClinicalTrials.gov/show/NCT00372008	Completed	Acrux DDS Pty Ltd	2007-04-30
NCT00365794	Effects of Testosterone Gel on Carbohydrate and Lipid Metabolism In Elderly Obese Men	https://ClinicalTrials.gov/show/NCT00365794	Completed	University of Southern California	2013-12-31
NCT00351819	Effects of Testosterone Replacement on Pain Sensitivity and Pain Perception	https://ClinicalTrials.gov/show/NCT00351819	Completed	Boston University	2012-11-30
NCT00349362	Testosterone for Men With Insulin Treated Type 2 Diabetes	https://ClinicalTrials.gov/show/NCT00349362	Completed	Barnsley Hospital	2008-10-31
NCT00345969	Exercise and Testosterone Therapy in Elderly Men With Physical Frailty	https://ClinicalTrials.gov/show/NCT00345969	Completed	Washington University School of Medicine	2009-02-28
NCT00290134	A Preliminary Clinical Study to Evaluate Fispemifene in the Treatment of Hypogonadism	https://ClinicalTrials.gov/show/NCT00290134	Completed	QuatRx Pharmaceuticals Company	NA
NCT00287586	Testosterone Replacement in Older Men and Atherosclerosis Progression	https://ClinicalTrials.gov/show/NCT00287586	Completed	Brigham and Women’s Hospital	2012-02-07
NCT00266864	Testosterone Replacement Therapy in Chronic Spinal Cord Injury	https://ClinicalTrials.gov/show/NCT00266864	Completed	VA Office of Research and Development	2012-08-31
NCT00244023	Co-Administering Testosterone With PDE5 Inhibitors in ED Patients Non Responders to PDE5 Inhibitors Alone	https://ClinicalTrials.gov/show/NCT00244023	Completed	SELARL du Dr Jacques BUVAT	2007-07-31
NCT00223860	Provocative Testing Using LHRH and hCG of the Pituitary-Gonadal Axis in Persons With Spinal Cord Injury.	https://ClinicalTrials.gov/show/NCT00223860	Completed	VA Office of Research and Development	2007-12-31
NCT00220298	Assessment of Long Term Treatment With Testosterone Undecanoate in Males With Hypogonadism	https://ClinicalTrials.gov/show/NCT00220298	Completed	Bayer	2007-10-31
NCT00202462	The Effect of Testosterone on Mood and Quality of Life	https://ClinicalTrials.gov/show/NCT00202462	Completed	Seattle Institute for Biomedical and Clinical Research	2005-12-31
NCT00194675	TRADE-Testosterone Replacement and Dutasteride Effectiveness	https://ClinicalTrials.gov/show/NCT00194675	Completed	University of Washington	2010-04-30
NCT00193700	Pharmacokinetic Evaluation of Testosterone Gel (1%)	https://ClinicalTrials.gov/show/NCT00193700	Completed	Solvay Pharmaceuticals	NA
NCT00193661	Observation Study of T-Gel (1%) in Treatment of Adolescent Boys With Hypogonadism	https://ClinicalTrials.gov/show/NCT00193661	Completed	Solvay Pharmaceuticals	2007-03-31
NCT00179517	Treatment of Sexual Dysfunction in Hypogonadal Men With Epilepsy With Testosterone and Either Anastrozole or Placebo	https://ClinicalTrials.gov/show/NCT00179517	Completed	Beth Israel Deaconess Medical Center	2008-04-30
NCT00161486	The Effects of Testosterone on Prostate Tissue (ACYP-1)	https://ClinicalTrials.gov/show/NCT00161486	Completed	University of Washington	2004-11-30
NCT00161421	Oral Androgens in Man-3 (ORAL T-3) Pharmacokinetics of Oral Testosterone	https://ClinicalTrials.gov/show/NCT00161421	Completed	University of Washington	2006-07-31
NCT00141492	Efficacy and Safety of Androgel in the Treatment of Hypogonadal and Low Testosterone Men With Type 2 Diabetes	https://ClinicalTrials.gov/show/NCT00141492	Completed	Solvay Pharmaceuticals	2007-06-30
NCT00140998	Estrogen Treatment (Oral vs. Patches) in Turner Syndrome	https://ClinicalTrials.gov/show/NCT00140998	Completed	Nemours Children’s Clinic	NA
NCT00138710	Short-term Effects of Aromatase Inhibition in Obese Men	https://ClinicalTrials.gov/show/NCT00138710	Completed	Rijnstate Hospital	2010-01-31
NCT00136695	Anastrozole Administration in Elderly Hypogonadal Men	https://ClinicalTrials.gov/show/NCT00136695	Completed	Massachusetts General Hospital	2008-10-31
NCT00119483	Older Men and Testosterone	https://ClinicalTrials.gov/show/NCT00119483	Completed	University Hospital of North Norway	NA
NCT00104572	Effects of Aromatase Inhibition Versus Testosterone in Older Men With Low Testosterone: Randomized-Controlled Trial.	https://ClinicalTrials.gov/show/NCT00104572	Completed	National Institutes of Health Clinical Center (CC)	2013-12-31
NCT00080483	Testosterone and Growth Hormone for Bone Loss in Men	https://ClinicalTrials.gov/show/NCT00080483	Completed	University of Pennsylvania	2010-09-30
NCT00048841	Prevention of Osteoporosis in Men With Prostate Cancer	https://ClinicalTrials.gov/show/NCT00048841	Completed	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	NA
NCT00004438	Leuprolide in Treating Adults With Hypogonadotropism	https://ClinicalTrials.gov/show/NCT00004438	Completed	FDA Office of Orphan Products Development	NA
NCT00004426	Leuprolide in Determining the Cause of Gonadotropin Deficiency	https://ClinicalTrials.gov/show/NCT00004426	Completed	FDA Office of Orphan Products Development	NA

Observational Studiess

#If less then 500 studies

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT03256292	Long-term Lifestyle Change and Testosterone Replacement	https://ClinicalTrials.gov/show/NCT03256292	Enrolling by invitation	Baylor College of Medicine	2021-08-31
NCT03254641	Calciotropic Effects After hCG Stimulation Test	https://ClinicalTrials.gov/show/NCT03254641	Active, not recruiting	Rigshospitalet, Denmark	2020-03-31
NCT03063125	Hypogonadism in Bladder Cancer	https://ClinicalTrials.gov/show/NCT03063125	Active, not recruiting	University of Kansas Medical Center	2020-05-30
NCT02728440	Effects of Gonadotropin Replacement Therapy on Metabolic Parameters in Patients With Hypogonadism	https://ClinicalTrials.gov/show/NCT02728440	Completed	Gulhane School of Medicine	2012-12-31
NCT02665559	Study of the Prevalence and Associated Factors With Hypogonadism in HIV + Men	https://ClinicalTrials.gov/show/NCT02665559	Completed	Tourcoing Hospital	2016-06-30
NCT01500447	Inherited Reproductive Disorders	https://ClinicalTrials.gov/show/NCT01500447	Recruiting	National Institutes of Health Clinical Center (CC)	NA
NCT02471157	Hormonal Predictors of Oncologic Surgery	https://ClinicalTrials.gov/show/NCT02471157	Completed	Weill Medical College of Cornell University	2016-10-31
NCT02434562	Development and Validation of in Vitro Cell-based Bioassays for Nuclear Receptor Activation	https://ClinicalTrials.gov/show/NCT02434562	Completed	Universitaire Ziekenhuizen Leuven	2016-09-30
NCT02248467	Study of the Effect of Testosterone Treatment on Metabolic Parameters and Urinary Symptoms in Bariatric Patients	https://ClinicalTrials.gov/show/NCT02248467	Completed	University of Florence	2017-12-31
NCT02240966	Symptoms and Clinical Signs of Hypogonadism in Testicular Cancer Survivors	https://ClinicalTrials.gov/show/NCT02240966	Completed	Rigshospitalet, Denmark	2016-07-31
NCT02062307	Bone Mineral Markers in Hypogonadism	https://ClinicalTrials.gov/show/NCT02062307	Completed	Gulhane School of Medicine	2013-07-31
NCT01511588	Hormonal Regulation of Puberty and Fertility	https://ClinicalTrials.gov/show/NCT01511588	Recruiting	National Institutes of Health Clinical Center (CC)	NA
NCT01758094	Plasma RBP Levels in Patients With Idiopathic Hypogonadotrophic Hypogonadism	https://ClinicalTrials.gov/show/NCT01758094	Completed	Gulhane School of Medicine	2012-08-31
NCT03747003	Gonadal Function in Young to Middle Aged HIV-infected Men	https://ClinicalTrials.gov/show/NCT03747003	Active, not recruiting	Azienda Ospedaliero-Universitaria di Modena	2017-12-31
NCT03484260	Association Between the Prevalence of Cardiovascular Risk Factors and New Use of Testosterone	https://ClinicalTrials.gov/show/NCT03484260	Completed	Bayer	2018-05-15
NCT03437109	Efficacy of Androgen Substitution for Hypogonadism in Men With Type 2 Diabetes Mellitus	https://ClinicalTrials.gov/show/NCT03437109	Completed	Besins Healthcare	2019-02-01
NCT01172366	A Study to Evaluate the Potential for Interpersonal Transfer of Testosterone Following Single Dose Application	https://ClinicalTrials.gov/show/NCT01172366	Completed	Acrux DDS Pty Ltd	2010-09-30
NCT01148433	Quality of Life With TESTIM®	https://ClinicalTrials.gov/show/NCT01148433	Completed	Ferring Pharmaceuticals	2011-06-30
NCT01143818	ESPRIT Study in Hypogonadal Men	https://ClinicalTrials.gov/show/NCT01143818	Completed	Abbott	2010-08-31
NCT00858650	Registry of Hypogonadism in Men	https://ClinicalTrials.gov/show/NCT00858650	Completed	HealthCore-NERI	2013-09-30
NCT00847314	Efficacy and Tolerability of Testogel/Nebido in Combination With Exercise and Diet in Hypogonadal Male Patients	https://ClinicalTrials.gov/show/NCT00847314	Completed	Bayer	2008-10-31
NCT00838838	Efficacy of Nebido on Bone Mineral Density (BMD) in Hypogonadal Paraplegic Patients With Confirmed Osteoporosis	https://ClinicalTrials.gov/show/NCT00838838	Completed	Bayer	2009-05-31
NCT01601171	The Genetic Investigation of Reproductive Disorders (Including Kallmann Syndrome)	https://ClinicalTrials.gov/show/NCT01601171	Recruiting	Centre Hospitalier Universitaire Vaudois	2022-03-31
NCT01914172	Health Needs of Patients With Kallmann Syndrome	https://ClinicalTrials.gov/show/NCT01914172	Completed	Centre Hospitalier Universitaire Vaudois	2014-03-31
NCT01703676	Epigenetics and Metabolic Disorders in Men With the Klinefelter Syndrome	https://ClinicalTrials.gov/show/NCT01703676	Completed	University Hospital Muenster	2012-05-31
NCT00624624	Follow-up of Serum Androgen Profile After Bariatric Surgery in Men With Obesity Related Hypogonadotropic Hypogonadism	https://ClinicalTrials.gov/show/NCT00624624	Completed	Rijnstate Hospital	2011-03-31
NCT00494169	Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders	https://ClinicalTrials.gov/show/NCT00494169	Recruiting	Massachusetts General Hospital	2023-05-31
NCT00483418	Survey of Testosterone Levels in Male Cancer Patients	https://ClinicalTrials.gov/show/NCT00483418	Completed	Beth Israel Medical Center	2009-12-31
NCT00472940	Prevalence of Hypogonadism in Male Cancer Patients	https://ClinicalTrials.gov/show/NCT00472940	Completed	Baylor College of Medicine	NA
NCT00425568	Transdermal Testosterone Gel/Effect on Erection Quality as Measured by DIR	https://ClinicalTrials.gov/show/NCT00425568	Completed	Lamm, Steven, M.D.	NA
NCT00410306	Use of Nebido® to Assess Tolerability and Treatment Outcomes in Daily Clinical Practice	https://ClinicalTrials.gov/show/NCT00410306	Completed	Bayer	2010-07-31
NCT00170339	Bone Density and Serum Testosterone in Male Methadone Maintained Patients	https://ClinicalTrials.gov/show/NCT00170339	Completed	Hennepin Healthcare Research Institute	NA
NCT00001412	Effects on the Brain of Lupron Induced Hypogonadotropic Hypogonadism With and Without Testosterone Replacement	https://ClinicalTrials.gov/show/NCT00001412	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00001275	Ovarian Follicle Function in Patients With Primary Ovarian Failure	https://ClinicalTrials.gov/show/NCT00001275	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00004335	Study of Gonadotropin-Releasing Hormone Pulse Frequency in Sexual Maturation and in the Menstrual Cycle	https://ClinicalTrials.gov/show/NCT00004335	Completed	National Center for Research Resources (NCRR)	NA

Registries

#If less then 500 registries

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT02042638	The Effects of Gonadotropin Replacement Therapy in Patients With Hypogonadism	https://ClinicalTrials.gov/show/NCT02042638	Completed	Gulhane School of Medicine	2013-08-31
NCT01793168	Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford	https://ClinicalTrials.gov/show/NCT01793168	Recruiting	Sanford Health	2100-12-31